With pharmaceuticals the FDA customarily insists that "class effects", meaning adverse effects and black-box warnings, apply to all drugs considered to belong to a category. It doesn't even matter if a brand new drug is far less likely to produce certain "class effects" than prior drugs in the same category, the exact same warnings must still be listed.
In other words, the implicit rule is that drugs or additives in a class are "guilty" of potentially causing an adverse effect unless thorough study provides evidence that a member of a class does not produce particular negative effects. It's a high bar for manufacturers to get over and it's seldom attempted.
The FDA can assume serious adverse effects of one artificial sweetener apply to others, if the others are officially in the same class of substances as the first.
In other words, the implicit rule is that drugs or additives in a class are "guilty" of potentially causing an adverse effect unless thorough study provides evidence that a member of a class does not produce particular negative effects. It's a high bar for manufacturers to get over and it's seldom attempted.
The FDA can assume serious adverse effects of one artificial sweetener apply to others, if the others are officially in the same class of substances as the first.