Except if you have a mouse like the Naga with more programmable buttons, they're all useless unless you use the software.
It works great on my MX518 so I don't have to use the terrible Logitech software to configure the extra buttons. :)
Regardless, I'm using the old, pre-Synapse drivers and they work ok.
Except if you have a mouse like the Naga with more programmable buttons, they're all useless unless you use the software.