No. 1 thing about Django that annoys me(1) is that the Admin-interface, in all it's awesomeness isn't modular and pluggable. I want to put CRUD+filtering lists on the non-admin part of the site, and can't seems to find a non-hacky way of doing it.
(1) The list thins out a lot after than. I agree with Zed that the apps-in-a-site structure is very cool.
In my experience, "simple CRUD" often gets complicated by permissions or other special cases, but generic views and modelforms are useful tools for hammering out a lot of the basics very very fast. Both of them allow for some degree of customization, but should be helpful in achieving what you want.
The admin annoys me for same reason. It's too awesome to throw away, but wasn't quite malleable enough. This is changing for the very much better in next release/trunk.
(1) The list thins out a lot after than. I agree with Zed that the apps-in-a-site structure is very cool.