Your Name (2016, Makoto Shinkai) and Ping Pong the Animation (2014, Masaaki Yuasa) are both IMO top notch (and the creators are active and have extensive oeuvres). The Shape of Voice (2016, Kyoto Animation (RIP)) was also much acclaimed. Of these, I recommend Ping Pong the most (and Yuasa's other works as well).
I suppose for more sci-fi/fantasy, Rebuild of Evangelion (2007-2021) might be interesting, although to me, its popularity in Japan and why the retelling was made is actually more interesting to me than the works themselves. It didn't win any particular awards or acclaim, but I was a fan of the incredibly stylish manga series, and I personally enjoyed the Blame! (2017, Hiroyuki Shesita) CGI anime film for those into the Japanese post-cyber-apocalypse sci-fi aesthetic.
I think these days, the economics of anime has driven more interesting work into series rather than features. Recently some memorable ones I've enjoyed are Steins;Gate (2011-2015, White Fox), Devilman: Crybaby (2018, Studio SARU), Cyberpunk: Edgerunners (2022, Trigger), Pluto (2023, M2), and Frieren (2023, Madhouse).
I suppose for more sci-fi/fantasy, Rebuild of Evangelion (2007-2021) might be interesting, although to me, its popularity in Japan and why the retelling was made is actually more interesting to me than the works themselves. It didn't win any particular awards or acclaim, but I was a fan of the incredibly stylish manga series, and I personally enjoyed the Blame! (2017, Hiroyuki Shesita) CGI anime film for those into the Japanese post-cyber-apocalypse sci-fi aesthetic.
I think these days, the economics of anime has driven more interesting work into series rather than features. Recently some memorable ones I've enjoyed are Steins;Gate (2011-2015, White Fox), Devilman: Crybaby (2018, Studio SARU), Cyberpunk: Edgerunners (2022, Trigger), Pluto (2023, M2), and Frieren (2023, Madhouse).