No. Good information can be behind a payed site, and possibly, more investigative. Free sites can sometimes be less verified or partial information. I think the goal would be to have the most accurate link possible, rather than many links that only contain a subset of the information.
Chemo post-histrophy would remove any lingering cancer cells effectively. Cancer cells need lots of fuel or they stop replicating, and this is what traditional chemo is great at stopping.
Is the idea that you would need less chemo after the tumor is broken up to remove any remaining cancer cells versus just starting out with chemo to remove the tumor?
Chemotherapy isn't always successful, and depends on the tumor's characteristics, but the idea is yes, less chemo. Histrophy is similar to resection, physically removing a tumor. I've seen chemo options for both scenarios with resectable cancers. For example, hormonal therapy is usually prescribed after resectable breast cancer, regardless of outcome. Or, chemo first to shrink the tumor, and have better surgical margins.
The keto diet is also very good for this because many (but not all) cancer cells can't metabolize ketones. However recent research from Columbia Medical School suggests that it can promote metastasis.
It's a good thing you edited for politeness because you seemed to be basing your understanding of what I said based on stuff you read on Reddit.
A number of studies show that, in humans, the keto diet (the medical keto diet[1] and not the meat heavy Internet version) causes metabolic stress in breast cancer cells and in several other types of cancer, due to their significantly increased metabolic needs. It's like the difference between a normal human and Michael Phelps during Olympic competition. The cancer cells can process ketones, but not efficiently enough to fuel their activity so they starve.
In humans this eventually results in the death or deactivation of the cancerous cells (deactivation being the primary way that tumors "adapt" to a starvation diet). There have been few, if any, reported cases of metastasis in the types of cancers studied in humans. This outcome is statistically significant enough that multiple cancer treatment centers recommend the medical keto diet to human patients as part of a treatment regime.
As mentioned, the recent study from 2024 shows that this type of metabolic stress can, in mice cause the cancerous cells to metastasize in a last-ditch attempt to survive. However, very little of the cancer research conducted on mice has applications to human cancers. For example, chemotherapy has also been shown to cause metastasis in mice, and a number of earlier studies attempting to replicate the keto research in humans shows that the keto diet in mice increases tumor growth, which is the opposite effect it has in humans.
[1] The medical keto diet is basically just fat and vitamins. No carbs, and minimal to no protein because protein can get converted into glucose by gluconeogenesis. It is not a diet anyone would want to be on longer than strictly necessary. One of my friends had stage 4 metastatic lung cancer, which she discovered during a company-sponsored mud run. Surgery was not an option and chemotherapy was not working. With less than 4 months to live, she went on the medical keto diet and the two-punch combo of keto and chemo put the cancer into remission for almost three years. (Note: She only maintained the diet for a few months after ending chemo treatment. Unfortunately not all of the cancer cells had died, some had merely deactivated. Four years after remission the cancer cells reactivated with a vengeance and she died the day after she started showing symptoms.)
No, not really. If you are just looking to work with the data you want to read about extracting from grib2 format. One of the faster ways off the ground is to use the Pywgrib2_s python package and iterate against the model files using python to extract the fields that are interesting. I have a container on docker hub that has pywgrib compiled with all its dependencies if you want to tinker.
there was an early version of something very much like windy, except that it is a globe that you can spin in 3d and expand,but with zero branding or fancy stuff, no idea what it was the url is.
and re: windy thanks for the reminder, I had dropped windy as it was breaking in my browser of choice, but it's working again
>> The first included students about to graduate, recent graduates, and those who have been working for less than a year (referred to as “fresh graduates”).
>> The second group consisted of people with more than a year of work experience, regardless of when they graduated (referred to as “earlier graduates”).
IMO, I think it breaks even, but eating out saves a lot of time! Healthier cooking at home? Yes. I studied this for myself (N=1), and my cooking is about US$10/meal give or take (asparagus, chicken, rice, water to drink). If you cook for two or more people, then I think cooking at home comes out ahead financially.
>cooking is about US$10/meal give or take (asparagus, chicken, rice, water to drink).
You must be eating an absolute TON to eat $10 worth of chicken, asparagus, and rice. I just checked the prices at Target and rice is $1.89 for 2 pounds, chicken thighs are $1.69 a pound. Asparagus is spendier at $5 for 1 pound.
How many pounds of chicken and asparagus are you eating? Even if you ate two pounds of chicken and the entire pound of asparagus you aren't hitting $10.
...and add the time for preparation, cleaning up etc.: Thats one of the most frustrating things when cooking for one person - you invest 45min to eat 5min and the rest is "organisation & logistics"
45 minutes is crazy. I have a chicken and rice dish I can make in 20 minutes (yes, I've timed myself because I'm weirdo and enjoy those chef shows). It takes 20 minutes because that's how long the rice takes. It can be faster if I use shrimp instead of chicken (more expensive though) and noodles instead of rice. It also makes ~3 servings.
Wow, i got downvoted for complaining about my cooking times on HackerNews, this is a real innovation:
so:
- 5 min walk to supermarket
- 10 min in there
- 5 min walk back home
- washing & cutting wedgetables 7 - 10 min
- maybe cutting some meat: 5 min on top
- eating 5 - 10 min
- cleaning up the kitchen 5 min
Haha...I didn't downvote you, but 45 minutes to cook seemed crazy to me unless you're making something new or complicated or you're socializing. You also kept eating separate from cooking in your first post.
I don't count the walk to the supermarket since even if you eat out almost every meal, you still tend to need to go to the grocery for items either way. And if you eat out, you still have to go there and back.
Cutting should be in parallel with cooking. Similar to cutting, cleaning should also be in parallel with cooking. For example, my knife and cutting board are washed, dried and put away before my sauce finishes simmering down.
That's why when it's just me I don't really do much cooking. I'll eat ultra-low prep stuff like toast (w/beans, hummus or avocado), bagged salad, frozen food, or grilled tofu.
>> Across a generation’s life course, early-life advantages are magnified through disparate occupational and social trajectories that lead to wide late-life disparities in financial and health resources, in a process first termed by Crystal and Shea as one of “cumulative advantage and disadvantage” (CAD; Crystal, 1982, 1986, 2020; Crystal et al., 1992, 2017; Crystal & Shea, 1990b; Dannefer, 1987, 1988). Dannefer (1987) described the trend of increasing inequality over the life course as the “Matthew effect,” applying a biblical dictum first used by Merton (1968), stating that “to he who has much, more is given, and to he who has little, even that is taken.” This ongoing process has also been described as an “obdurate tendency” for increasing inequality over the life course (Dannefer, 2020).
If I think back (way back), my own leap into "real job" after university was difficult, intimidating. I enjoyed having no real responsibilities, and tried to get the "fun" jobs even though it didn't pay much.
Eventually I had to. The first job I had was at an insurance company and I left it after 3 days. It was so boring, so serious, and no fun! Later, after more interviewing and some panicking, I found a job at a community college that had a little fun, but was much more "real world". It helped me transition.
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